Reference Tool
Compare Compounds
Place up to three reference compounds side by side to compare their molecular profile, pharmacokinetics, and handling.
| Attribute | semaglutide | cagrilintide | retatrutide |
|---|---|---|---|
| Field of Medicine | Endocrinology · Metabolic Research | Endocrinology · Metabolic Research | Endocrinology · Metabolic Research |
| Category | incretin | incretin | incretin |
| Formula | C187H291N45O59 | — | — |
| Molecular Weight | 4113.6 Da | ~3800 Da | ~4731 Da |
| Sequence | 31-amino-acid GLP-1 analog with C18 fatty diacid | Long-acting amylin analog | 39-amino-acid triple agonist (GLP-1 / GIP / glucagon) |
| CAS Number | 910463-68-2 | — | — |
| Half-Life | ~7 days | ~7–8 days | ~6 days |
| Route (research) | Subcutaneous in research models | Subcutaneous in research models | Subcutaneous in research models |
| Onset / Steady-state | Steady-state after ~4–5 weeks of weekly dosing | — | — |
| Lyophilized Storage | −20°C long term; 2–8°C short term (weeks). Protect from light. | −20°C long term; 2–8°C short term (weeks). Protect from light. | −20°C long term; 2–8°C short term (weeks). Protect from light. |
| Reconstituted Storage | 2–8°C, generally up to 14–28 days depending on compound. | 2–8°C, generally up to 14–28 days depending on compound. | 2–8°C, generally up to 14–28 days depending on compound. |