Park Ave Peptides — Clinical Reference Library — For Professional Use Only

Dermatology · Pigmentation Research
cGMP facility · Third-party tested · Cold-chain shipping · 24-hour COA on request
Reference Compound
Educational reference for Melanotan II. Scroll down for molecular profile, pharmacokinetics, mechanism, applications, and handling.
At a Glance
ShowQuality Documentation
Lot PAP-MELANO-240118-A01 — Reference
Field of Medicine — Dermatology · Pigmentation Research
Dermatology and Melanocortin-System Research.
Melanotan II is a synthetic cyclic heptapeptide analog of α-MSH originally developed at the University of Arizona as a research tool for melanocortin-receptor pharmacology and photoprotection studies.
Melanotan II is a non-selective agonist at MC1R, MC3R, MC4R, and MC5R. MC1R activation drives eumelanin production in melanocytes; MC4R activation in CNS nuclei influences appetite and sexual arousal pathways, accounting for the breadth of its observed effects.
Reference Compound
Melanotan II
02 — Science
03 — Pathway
Mechanism summaries for Melanotan II are drawn from peer-reviewed literature describing receptor binding, signaling pathways, and observed activity in preclinical models.
04 — Lab Reference
For licensed research and clinical evaluation only. Not dosing guidance.
Reconstitution
Bacteriostatic water (0.9% benzyl alcohol) or sterile water. Add diluent slowly along the vial wall — do not inject directly onto the lyophilized cake. Swirl gently until fully dissolved.
Storage
Lyophilized: −20°C long term; 2–8°C short term (weeks). Protect from light.Reconstituted: 2–8°C, generally up to 14–28 days depending on compound.
Quality
≥99% purity by HPLC. Identity confirmed by mass spectrometry. Independent third-party verification on every lot. COA available per lot.
Handling notes —Avoid repeated freeze–thaw cycles. Do not shake vigorously after reconstitution.
Need a full protocol brief?
Reconstitution worksheets, concentration reference cards, and sample COA for verified accounts.
05 — Common Questions
Melanotan II is presented here as a reference compound for clinicians and researchers. Regulatory status varies by jurisdiction and indication — see the official drug databases (FDA, EMA) for current approval information.
Yes. A lot-specific COA documenting identity and purity by HPLC and mass spectrometry is available on request through the Request Information form.
Each lot is analyzed by reverse-phase HPLC for purity and confirmed by mass spectrometry for identity. Independent third-party laboratory verification is performed on every lot.
Store the lyophilized vial refrigerated for short-term use, or frozen at −20°C for long-term storage. Once reconstituted, refrigerate and protect from light.
06 — Citations
The following sources are representative of the literature describing Melanotan II. A full annotated citation list with PubMed identifiers is available on request.
See also the glossary of research terms and the full peptide library.
Comparative Reference
See molecular profile, pharmacokinetics, and handling next to related compounds in the same family.
Often Researched Alongside
cGMP facility · Third-party tested · Cold-chain shipping · 24-hour COA on request