Mitochondrial · 7 min
Mitochondrial Peptides: SS-31, MOTS-c, and Cellular Bioenergetics
SS-31 (Elamipretide)
A small peptide that selectively binds cardiolipin on the inner mitochondrial membrane. By stabilizing cristae structure it preserves electron transport chain efficiency in models of mitochondrial dysfunction.
MOTS-c
A 16-amino-acid peptide encoded by the mitochondrial 12S rRNA. As a mitochondrial-derived peptide it represents an entirely separate signaling axis with effects on metabolic homeostasis described in published research.
Research context
Mitochondrial peptides are an emerging class. Reference-grade material with verified purity and identity is essential for reproducible work given the small quantities typically used.